Evaluation of Ovarian Reserve by Measurement of the Serum Levels of Anti-Mullerian Hormone and Follicle-Stimulating Hormone in Intracytoplasmic Sperm Injection Cycles
نویسندگان
چکیده مقاله:
Background It is important to evaluate ovarian reserves prior to intracytoplasmic sperm injection (ICSI) treatment. The aim of this study is to determine the accuracy of anti-mullerian hormone (AMH) as a marker for ovarian reserve and to compare it with day-3 serum follicle-stimulating hormone (FSH) levels. MaterialsAndMethods In this analytic, corss-sectional study, sequential sampling was done on 70 infertile women who underwent ICSI treatment at Imam Khomeini Hospital, Ahvaz, Iran. Initially, 5cc of venous blood was drawn from each patient to measure serum AMH and FSH levels on the day-3 cycle. Patients were divided into two subgroups according to the numbers of oocytes retrieved. Patients were classified as good responders if there were four or more oocytes retrieved, whereas patients with less than four oocytes were poor responders. Results The basal AMH level correlated with the number of oocytes retrieved (linear Pearson correlation coefficient=0.599), however the basal FSH level had a weakly reverse correlation (correlation coefficient = -0.11). AMH levels had a sensitivity of 85% and specificity of 61.5%, with a cutoff value equal to 2.3 ng/ml which was higher than FSH. Conclusion AMH serum levels are good predictors of ovarian reserve in comparison with FSH.
منابع مشابه
evaluation of ovarian reserve by measurement of the serum levels of anti-mullerian hormone and follicle-stimulating hormone in intracytoplasmic sperm injection cycles
background: it is important to evaluate ovarian reserves prior to intracytoplasmic sperm injection (icsi) treatment. the aim of this study is to determine the accuracy of anti-mullerian hormone (amh) as a marker for ovarian reserve and to compare it with day-3 serum follicle-stimulating hormone (fsh) levels. materials and methods: in this analytic, corss-sectional study, sequential sampling was...
متن کاملAge-Specific Serum Anti-Mullerian Hormone and Follicle Stimulating Hormone Concentrations in Infertile Iranian Women
Background Anti-Müllerian hormone (AMH) is secreted by the granulosa cells of growing follicles during the primary to large antral follicle stages. Abnormal levels of AMH and follicle stimulating hormone (FSH) may indicate a woman’s diminished ability or inability to conceive. Our aim is to investigate the changes in serum AMH and FSH concentrations at different age groups and its correlation w...
متن کاملThe Correlations of Anti-Mullerian Hormone, Follicle-Stimulating Hormone and Antral Follicle Count in Different Age Groups of Infertile Women
متن کامل
Serum Anti-Mullerian Hormone, Serum Follicle Stimulating Hormone and Serum Estradiol in the Prediction of Ovarian Reserve: A Comparative Study
Objective: Our study was undertaken to find if any correlation exists between levels of Anti-Mullerian (AMH), follicle stimulating hormone (FSH) and estradiol (E2), with the ovarian reserve. Methods: A Randomized, prospective study was conducted at Infertility Clinic,Department of Obstetrics & Gynecology, Mahatma Gandhi Medical College and Hospital,Jaipur on 105 patients aged 25-40 years underg...
متن کاملassessment of ovarian reserve: anti?mullerian hormone versus follicle stimulating hormone
background: this study aimed to evaluate the strength of anti?mullerian hormone (amh) and follicle stimulating hormone (fsh) in reflecting the antral follicle count (afc) in infertile females. materials and methods: this cross?sectional study was conducted on 160 females, visiting infertility clinic for assisted reproduction. serum samples collected on the 3rd day of the cycle were assayed for ...
متن کاملAssessment of ovarian reserve: Anti-Mullerian hormone versus follicle stimulating hormone
BACKGROUND This study aimed to evaluate the strength of anti-Mullerian hormone (AMH) and follicle stimulating hormone (FSH) in reflecting the antral follicle count (AFC) in infertile females. MATERIALS AND METHODS This cross-sectional study was conducted on 160 females, visiting infertility clinic for assisted reproduction. Serum samples collected on the 3rd day of the cycle were assayed for ...
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عنوان ژورنال
دوره 4 شماره 2
صفحات 57- 60
تاریخ انتشار 2010-06-01
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